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- N. S. Dighe
- S. B . Dighe
- S. B. Bhawar
- R. B. Saudagar
- V. M. Gaware
- M. B. Hole
- V. B. Tambe
- Jayashri Pattan
- B. P. Kapadnis
- S. V. Devhare
- S. A. Nirmal
- R. A. Rub
- Subhash C. Mandal
- P. M. Gaikwad
- R. S. Kalkotwar
- H. V. Shinde
- R. L. Hullolikar
- J. S. Pattan
- S. H. Kale
- S. V. Hiremath
- A. N. Merekar
- D. S. Musmade
- R. K. Godge
- M. C. Damle
- P. N. Kendre
- S. N. Lateef
- P. J. Burange
Journals
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Pattan, S. R.
- Chikungunya Disease: A Review
Abstract Views :264 |
PDF Views:2
Authors
N. S. Dighe
1,
S. R. Pattan
1,
S. B . Dighe
1,
S. B. Bhawar
1,
R. B. Saudagar
2,
V. M. Gaware
1,
M. B. Hole
1,
V. B. Tambe
1
Affiliations
1 Pravara Rural College of Pharmacy, Pravaranagar, A/P-Loni (413736), Tal- Rahata, Dist.-Ahmednagar, Maharashtra, IN
2 R. G. Sapakal College of Pharmacy, Nasik, Maharashtra, IN
1 Pravara Rural College of Pharmacy, Pravaranagar, A/P-Loni (413736), Tal- Rahata, Dist.-Ahmednagar, Maharashtra, IN
2 R. G. Sapakal College of Pharmacy, Nasik, Maharashtra, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 1 (2009), Pagination: 7-12Abstract
Chikungunya virus is an insect-borne virus, of the genus Alphavirus, that is transmitted to humans by virus-carrying Aedes mosquitoes. The virus causes an illness with symptoms similar to dengue fever with an acute febrile phase of the illness which lasts only two to five days. Infection can affect the nervous system or the musculo-skeletal system. General symptoms include fever, headache, maculopapular rash, arthralgia, myalgia, photophobia and lymphadenopathy. Virus isolation provides the most definitive diagnosis. The most effective means of prevention are protection against contact with the disease-carrying mosquitoes and mosquito control. NSAIDs, chloroquine and DNA vaccine are the effective medicines.Keywords
Chikungunya, Aedes Mosquitoes, Fever, Chloroquine.
References
- De Lamballerie X, et al.. "Chikungunya virus adapts to tiger mosquito via evolutionary convergence: a sign of things to come?". Virol. J. 2008; 5: 33.
- Powers AM, Logue CH. "Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus" . J. Gen. Virol. 2007; 88: 2363–77.
- Sourisseau M, Schilte C, Casartelli N, et al. "Characterization of reemerging chikungunya virus". PLoS Pathog. 2007 ; 3 (6): 89.
- ENVIS News Letter, Issue 2, September, 2006.
- Robinson MC. "An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. I. Clinical features". Trans. R. Soc. Trop. Med. Hyg. 1955; 49 (1): 28–32.
- Lumsden WH. "An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. II. General description and epidemiology". Trans. R. Soc. Trop. Med. Hyg. 1955; 49 (1): 33–57.
- Tsetsarkin KA, Vanlandingham DL, McGee Ce et al., "A Single Mutation in Chikungunya Virus Affects Vector Specificity and Epidemic Potential". PLoS Pathog 2007; 3 (12): e201.
- ProMED-mail; Chikungunya virus: genetic change. ArchiveNumber 2007; 1209-3973.
- Thai Rath. "Trang hospital found Chikungunya transmitted from a mother to her foetus". 2009
- Wadia RS. A neurotropic virus (chikungunya) and a neuropathic aminoacid (homocysteine). Annals of Indian Academy of Neurology. 2007 Oct; 10(4): 198-213.
- Powers AM, Brault AC, Tesh RB, Weaver SC. Reemergence of chikungunya and o’nyong-nyong viruses: evidence for distinct geographical lineages and distant evolutionary relationships. Journal of General Virology. 2000 Feb; 81(Pt 2): 471-9.
- Strauss, J. H. and Strauss, E. G. Evolution of RNA viruses. Annual Review of Microbiology 1988; 42, 657-683.
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- http://www.who.int/csr/don/2006_02_17a/en/index.html
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- World Health Organization. Outbreak and spread of chikungunya. Weekly Epidemiological Record 2007; 82 (47): 409-415.
- Krishna MR, Reddy MK and Reddy SR. Chikungunya outbreaks in Andhra Pradesh, South India. Current Science 2006; 91(5): 570-571.
- World Health Organization-South-East Asia Regional Office. Chikungunya Fever, a re-emerging Disease in Asia. http://www.searo.who.int/en/Section10/Section2246.htm accessed 21 October 2008.
- Chhabra M, Mittal V, Bhattacharya D, Rana U, Lal S (). "Chikungunya fever:". Indian J Med Microbiol 2008; 26 (1): 5–12.
- Taubitz W, Cramer JP, Kapaun A, et al. "Chikungunya feverin travelers: clinical presentation and course". Clin. Infect. Dis. 2007; 45 (1): e1–4.
- WHO - Laboratory Diagnosis of Chikungunya Fevers". http://www.searo.who.int/EN/Section10/Section2246_12902.htm. Retrieved 2008-07-11.
- Chikungunya fever diagnosed among internationaltravelers—United States, 2005-2006". MMWR Morb. Mortal. Wkly. Rep. 55 (38): 1040–2. September 29, 2006.
- "Chikungunya - Fact sheet". European Centre for Disease Prevention and Control. 2008-01-23.
- Mahendradas P, Ranganna SK, Shetty R, et al. Ocular manifestations associated with chikungunya. Ophthalmology. 2008 Feb; 115(2):287-91.
- Kennedy AC, Fleming J, Solomon L. Chikungunya viral arthropathy: a clinical description. Journal of Rheumatology. 1980 Mar-Apr; 7 (2): 231-6.
- Martin Enserink. "Chikungunya: No Longer a Third World Disease". Science 2007; 318 (5858): 1860–1861.
- Robinson MC. "An epidemic of virus disease in Southern Province, Tanganyika Territory, in 1952-53. I. Clinical features". Trans. R. Soc. Trop. Med. Hyg. 1955; 49 (1): 28–32.
- Edelman R, Tacket CO, Wasserman SS, et al. "Phase II safety and immunogenicity study of livechikungunya virus vaccine TSI-GSD-218". Am. J. Trop. Med. Hyg. June 2000; 62 (6): 681–5.
- Muthumani K, Lankaraman KM, Laddy DJ, et al. "Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus". Vaccine 2008; 26 (40): 5128–34.
- Couderc T, Khandoudi N, Grandadam M, et al. Prophylaxis and therapy for Chikungunya virus infection. 2009; 200:516–523.
- Vanlandingham DL, Hong C, Klingler K, et al. "Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoes". Am J Trop Med Hyg 2005; 72 (5): 616–21.
- A Study of the Impact of Multimedia-CD Programme on Environmental Hygiene, Allergy and Aspergillosis amongst Professional Groups at Belgaum
Abstract Views :266 |
PDF Views:0
Authors
Affiliations
1 Pravara Rural College of Pharmacy, At post- Loni Tal- Rahata, Dist-Ahamadnagar, Maharashtra state, IN
2 Department of Microbiology, Pune University, Pune, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, (MS), IN
1 Pravara Rural College of Pharmacy, At post- Loni Tal- Rahata, Dist-Ahamadnagar, Maharashtra state, IN
2 Department of Microbiology, Pune University, Pune, Maharashtra, IN
3 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, (MS), IN
Source
Research Journal of Science and Technology, Vol 1, No 1 (2009), Pagination: 25-28Abstract
In the last two decades allergic infections have became more because of modernizations, change of life style and industrializations. It is reported that more than 9 million children under the age of 18 suffer from allergies and asthma. Belgaum is the district where humidity is quite high (20-50%).Mold is the commonest problem in rainy season. Mold spores may cause allergic reactions or asthma attacks in sensitive people. The study was conducted during 2006-2008in professional groups at Belgaum district, Karnataka. Professional groups included Computer Operators, Bank Employees and Lab-Technicians from Belgaum. Multimedia package-CD and reading material-Booklet were prepared after extensive references about allergy and Aspergillosis and it's preventions. Questionnaire was designed to assess the knowledge of respondents. Pretest questionnaire and after exposing the respondents to media post questionnaire were collected and analysed by statistical methods. It was observed that multimedia CD was found to be more efficient (20%-25%) and attractive in disseminating the knowledge regarding the Allergy and Aspergillosis.Keywords
Allergy, Allergic Aspergillosis, Mold Preventions, HEPA Filters.- Pharmacognostic Study of Aerial Parts of Celosia argentea Linn
Abstract Views :182 |
PDF Views:0
Authors
S. V. Devhare
1,
S. A. Nirmal
1,
R. A. Rub
2,
N. S. Dighe
3,
S. R. Pattan
3,
Subhash C. Mandal
4,
P. M. Gaikwad
5
Affiliations
1 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, M.S., IN
2 Department of Pharmacognosy, Allana College of Pharmacy, Pune, M.S., IN
3 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, M.S., IN
4 Pharmacognosy and Phytotherapy Research Laboratory, Depatment of Pharmaceutical Technology, Jadavpur University, Kolkata, IN
5 Department of Pharmacoloy, PDVVP College Of Pharmacy, Ahmednagar, M.S., IN
1 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar, M.S., IN
2 Department of Pharmacognosy, Allana College of Pharmacy, Pune, M.S., IN
3 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, M.S., IN
4 Pharmacognosy and Phytotherapy Research Laboratory, Depatment of Pharmaceutical Technology, Jadavpur University, Kolkata, IN
5 Department of Pharmacoloy, PDVVP College Of Pharmacy, Ahmednagar, M.S., IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 2 (2009), Pagination: 134-136Abstract
Celosia argentea Linn (Amaranthaceae) grows as a weed during rainy season throughout India and other tropical regions of the world such as Sri Lanka, South Asia, Africa and America. It is used traditionally for the treatment of jaundice, gonorrhea, inflammations, wounds, itching, diarrhea, blood diseases, mouth sores, and fever. It is also having an antipyretic, antidiabetic, antibacterial, diuretic, hepatoprotective, antimicrobial, and antimetastatic properties.
Objective of present work is to standardize the aerial parts by morphology, microscopy and various physical constants. The morphology, microscopy, determination of various physical constants viz. ash values, extractive values, moisture content and phytochemical screening were performed.
Morphological study reveals that the leaf is green, linear-lanceolate, ovate, acute and entire; the stem is yellowish green, erect, simple with grooved branches, flowers are first pinkish afterward glistering white in color, seeds are black, polished and shining. Microscopically leaf shows presence of chollenchyma, 3-4 vascular bundles at the center, palisade cells on upper side only; and microscopically stem shows the presence of xylem vessel, cortex, vascular bundles and pith.
Total ash, acid insoluble ash, water soluble ash and sulphated ash of aerial parts was found to be 14.5 % w/w, 2.0 % w/w, 3.0 % w/w and 20.0 %w/w respectively. Water-soluble and alcohol soluble extractive values of aerial parts were found to be 16.2 % w/w, 6.0%w/w respectively. Moisture content of aerial parts was found to be 11.0 % w/w.
- Analgesic Activity of Tamarindus indica
Abstract Views :173 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, IN
2 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, IN
1 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, IN
2 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni (413736), Maharashtra, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 1 (2009), Pagination: 69-71Abstract
Tamarindus indica (Caesalpiniaceae) bark is used in the treatment of pain traditionally, present work was undertaken to prove this scientifically by using suitable animal screening models as hot plate test and acetic acid induced writing test at the dose of 50 mg/kg, i.p. Petroleum ether extract showed significant increase in reaction time as compared to other extracts. Preliminary phytochemical test showed presence of sterols and triterpenes in the extract; hence these compounds might be responsible for analgesic activity.- Significance of Fluorine in Medicinal Chemistry:A Review
Abstract Views :189 |
PDF Views:0
Authors
Affiliations
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, M.S, IN
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, M.S, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 4 (2009), Pagination: 376-379Abstract
Fluorine is second smallest element in periodic table. It has many pharmacological activities with different substituted heterocycles. It has attracted the attention of Medicinal Chemist for its versatile and significant activities. This review explains the significance of presence of fluorine in various Medicinal compounds. The medicinal importance, use of the drugs containing fluorine is listed.Keywords
Fluorine, Haloperidol, Progabide.- Synthesis and Evaluation of Some New Phenyl Thiazole Derivatives for Their Anti-Microbial Activities
Abstract Views :154 |
PDF Views:0
Authors
S. R. Pattan
1,
R. L. Hullolikar
1,
J. S. Pattan
2,
N. S. Dighe
1,
M. B. Hole
1,
S. H. Kale
1,
S. B. Bhawar
3
Affiliations
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Department of Biotechnology, P V P Science College, Pravaranagar, Loni-413713, IN
3 Department of Pharmacology, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Department of Biotechnology, P V P Science College, Pravaranagar, Loni-413713, IN
3 Department of Pharmacology, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 3 (2009), Pagination: 292-296Abstract
Fifteen novel derivatives of phenyl thiazole derivatives were synthesized. The synthesized compounds were tested for their preliminary tests, physical constants, TLC, solubility, etc. the structures of the final compounds were confirmed by IR, 1H-NMR Spectra and CHN analysis. The proposed compounds were screened for their antimicrobial, antifungal, activities with the standard drugs.- Synthesis and Evaluation of Some New Substituted 1, 4-Dihydropyridine Derivatives and Their Anti-Inflammatory Activity
Abstract Views :152 |
PDF Views:0
Authors
S. R. Pattan
1,
N. S. Dighe
1,
S. V. Hiremath
2,
A. N. Merekar
3,
V. M. Gaware
1,
D. S. Musmade
1,
P. M. Gaikwad
4
Affiliations
1 Dept of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Dept of Pharmacology, J.N Medical College, Belgaum, IN
3 Dept of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
4 Dept of Pharmacology, Pd. Dr. Vitthalrao Vikhe Patil College of Pharmacy, Ahmednagar, IN
1 Dept of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
2 Dept of Pharmacology, J.N Medical College, Belgaum, IN
3 Dept of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, Loni-413713, IN
4 Dept of Pharmacology, Pd. Dr. Vitthalrao Vikhe Patil College of Pharmacy, Ahmednagar, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 3 (2009), Pagination: 310-313Abstract
A new series if substituted 1, 4-Dihydropyridine derivatives were synthesized and the structures of these compounds were established on the basis of spectral and elemental analysis. All the compounds were evaluated for anti-inflammatory activity by paw edema, xylene induced ear edema and cotton wool granuloma methods. Compounds C4, C5, C6, C7 and C9 have been found to exhibit excellent anti-inflammatory activity.Keywords
1, 4-Dihydropyridine, Anti-Inflammatory, CHN Analysis.- RP- HPLC Method for Simultaneous Estimation of Pseudoephidrine Sulphate and Desloratidine from Bulk and Tablets
Abstract Views :155 |
PDF Views:0
Authors
Affiliations
1 Pravara Rural College of Pharmacy, Pravaranagar, Dist. Ahemadnagar 413 736. (MS), IN
1 Pravara Rural College of Pharmacy, Pravaranagar, Dist. Ahemadnagar 413 736. (MS), IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 139-142Abstract
A simple, selective, rapid, precise and economical reverse phase high-pressure liquid chromatographic method has been developed for the simultaneous estimation of Pseudoephidrine sulphate and Desloratidine from pharmaceutical formulation by using internal standard Nabumetone. The method was carried out on a HiQ sil C18 W (250mm x 4.6 mm) column, with a mobile phase consisting of Acetonitrile: Methanol :Ammonium acetate (45:40:15 v/v) at a flow rate of 1.5 ml/min. Detection was carried out at 265 nm. The retention time of Pseudoephidrine sulphate, Desloratidine, and Nabumetone were 2.067, 3.050 and 3.750min. Respectively. The developed method was validated in terms of accuracy, precision, linearity, Limit of detection, Limit of quantitation. The proposed method can be used for estimation of these drugs in combined dosage form for routine analysis.Keywords
Pseudoephidrine Sulphate, Desloratidine, Nabumetone, RP-HPLC.- Synthesis and Biological Evaluation of Some Substituted Amino Thiazole Derivatives
Abstract Views :149 |
PDF Views:0
Authors
Affiliations
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, IN
2 Department of Pharmacognosy, Pravara Rural College of pharmacy, Pravaranagar, IN
3 Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, IN
1 Department of Medicinal Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, IN
2 Department of Pharmacognosy, Pravara Rural College of pharmacy, Pravaranagar, IN
3 Department of Pharmaceutics, Pravara Rural College of Pharmacy, Pravaranagar, IN
Source
Asian Journal of Research in Chemistry, Vol 2, No 2 (2009), Pagination: 196-201Abstract
Thiazoles and their derivatives exhibit a wide variety of biological activities like antidiabetic, anti inflammatory, anticonvulsants etc.
In the present study we have synthesized some substituted thiazoles. These compounds were evaluated for various biological activities like Anti-diabetic,anti-inflammatory,anti-fungal activity.